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ACE2 Recombinant Rabbit Monoclonal Antibody
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage of angiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity. Acts as a receptor for SARS coronavirus/SARS-CoV. Acts as a receptor for Human coronavirus NL63/HCoV-NL63.
Specifications
- Catalog No.
- BX50175
- Clone No.
- BP6153
- Application
- IHC-P
- Subcellular location
- Membrane and Secreted
- Control
- Testis
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide within Human ACE2 aa 750-850. The exact sequence is proprietary.
Reference
1. Donoghue M, et al. Circ. Res. 87:E1-E9(2000).
2. Hofmann H, et al. Natl. Acad. Sci. U.S.A. 102:7988-7993(2005).
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