Cytokeratin 6 Recombinant Rabbit Monoclonal Antibody

Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16.Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests.Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

Specifications

Catalog No.
BX50060
Clone No.
BP6065
Application
IHC-P
Subcellular location
Cytoplasm
Control
Esophagus cancer
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Synthetic peptide corresponding to Cytokeratin 6 residues within aa464-564 of Cytokeratin 6 was used as an immunogen.

Reference

1.R Moll et al. Histochem Cell Biol (2008) 129:705–733.
2.R Moll et al. Cell, Vol. 31, 1 l-24, November 1982.

Support Documents

Order

  • E-mail : sales@biolynx.cn

Contact Us

Address
Hangzhou Bailing (Biolynx)  Biotechnology Co., Ltd. Room 1303 Bldg 5, #688 Bin’an Road Tianhe High-tech Park, Binjiang District Hangzhou, Zhejiang, China
310052
Phone & Fax
+86 571 88177680
+86 571 88177681
Web & Mail
Email:sales@biolynx.cn
www.biolynxtec.com

Follow Us

Scan QR Codes on Your Phone