Human chorionic gonadotropin antibody (hCG) is a glycoprotein hormone synthesized in syncytiotrophoblastic cells of placenta and in certain trophoblastic tumors. The hormone-specific alpha chains have molecular weights of 13 kDa.HCG is found in moles and choriocarcinoma, chorionic components of germ cell tumours, and syncytiotrophoblast like cells in seminoma/dysgerminoma and embryonal carcinoma.In diagnostic pathology, hCG is a useful marker for classification of germ cell tumours, identification of extragonadal germ cell tumours.
Synthetic peptide corresponding to residues within aa1-100 of hCG was used as an immunogen.
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