Breast Carcinoma
Breast
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Mammaglobin Recombinant Rabbit Monoclonal Antibody
Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.
Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally.
Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.
Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally.
Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.
Specifications
- Catalog No.
- BX50121
- Clone No.
- BP6125
- Application
- IHC-P
- Subcellular location
- Cytoplasm
- Control
- Breast Carcinoma
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Recombinant fragment corresponding to Human Mammaglobin was used as an immunogen.
Reference
1.Fanger GR et al. Tumour Biol 23:212-21 (2002).
2.Han JH et al. Arch Pathol Lab Med 127:1330-4 (2003).
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