CD3 Recombinant Rabbit Monoclonal Antibody
Cluster of differentiation 3 (CD3) is a multimeric protein complex, known historically as the T3 complex, and is composed of four distinct polypeptide chains; epsilon (ε), gamma (γ), delta (δ) and zeta (ζ), that assemble and function as three pairs of dimers (εγ, εδ, ζζ). The CD3 complex serves as a T cell co-receptor that associates noncovalently with the T cell receptor (TCR).CD3 antigen appearance at all stages of T cell development, and makes it an ideal T cell marker for both the detection of normal T cells and T cell neoplasms (lymphomas and leukemias).
Specifications
- Catalog No.
- BX50034
- Clone No.
- BP6039
- Application
- IHC-P
- Subcellular location
- Membrane
- Control
- Tonsil
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide corresponding to CD3E residues within aa100-200 of CD3E was used as an immunogen.
Reference
1.Smith-Garvin JE, et.al, Annu Rev Immunol. 2009;27:591-619.
2.Salvadori S, et.al, J Immunol. 1994 Dec 1;153(11):5176-82.
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