Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Specifications
Catalog No.
BX50234
Clone No.
BP6211
Application
IHC-P
Subcellular location
Membrane
Control
Plasmacytoma
Recommended method
HIER
Volume
100μl/vial, 1ml/vial
Dilution
1:100-1:200
Immunogen
Full length protein corresponding to Human BCMA.
Reference
1. Reimer M et cm. BMC Dev Biol 19:16 (2019).
2. Tahara N et cm. Development 146:N/A (2019).