MHC II (DR α chain) Recombinant Rabbit Monoclonal Antibody
Major histocompatibility complex class II (MHC class II) molecules are heterodimeric, transmembrane glycoproteins expressed on the surface of antigen-presenting cells such as macrophages, dendritic cells, and B cells. Expression can also be induced on other cell types through interferon-γ signaling. Prior to being displayed on the cell membrane, MHC class II molecules are loaded with exogenous peptide antigens approximately 15-24 amino acids in length that were derived from endocytosed extracellular proteins digested in the lysosome.
Specifications
- Catalog No.
- BX50193
- Clone No.
- BP6171
- Application
- IHC-P
- Subcellular location
- Membrane
- Control
- Tonsil
- Recommended method
- HIER
- Volume
- 100μl/vial, 1ml/vial
- Dilution
- 1:100-1:200
- Immunogen
- Synthetic peptide near C-terminal residues in Human MHC Ⅱ(DR α chain) was used as an immunogen.
Reference
1. Temponi, M. et al. J Immunol Methods 161 (1993) .
2. Ting, J.P. and Trowsdale, J. Cell 109 Suppl (2002) .
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